Useful Papers

  • Myopia control

Short-term and long-term changes in corneal power are not correlated with axial elongation of the eye induced by orthokeratology in children

Jacinto Santodomingo-Rubido et al

In this study, it was assessed the relationship between short-term and long-term changes in power at different corneal locations relative to the change in central corneal power and the 2-year change in axial elongation relative to baseline in white European children wearing orthokeratology contact lenses (Ortho-K).
The result showed the reduction in central corneal power and relative increase in paracentral and pericentral power induced by OK over 2 years were not significantly correlated with concurrent changes in axial length of white European children.

https://insights.ovid.com/pubmed?pmid=27763910


  • Myopia control

Short- and Long-Term Changes in Corneal Aberrations and Axial Length Induced by Orthokeratology in Children Are Not Correlated

Jacinto Santodomingo-Rubido et al.

The study was conducted to assess the correlation between changes in corneal aberrations and the 2-year change in axial length in children fitted with orthokeratology contact lenses (ortho-K).
It was found short-term and long-term ortho-K lens wear induces significant changes in corneal aberrations that are not significantly correlated with changes in axial elongation after 2-years.

https://insights.ovid.com/crossref?an=00140068-201711000-00005


  • Myopia control

Long-term Efficacy of Orthokeratology Contact Lens Wear in Controlling the Progression of Childhood Myopia

Jacinto Santodomingo-Rubido, César Villa-Collar, Bernard Gilmartin, Ramón, Gutiérrez-Ortega & Keiji Sugimoto

The study was conducted over 7 years to compare the axial length growth of white European myopic children from 6 to12 years old wearing orthokeratology contact lenses (ortho-K) to a control group over a 7-year period. The axial length growth of ortho-K group was 33% slower than the on

https://www.tandfonline.com/doi/full/10.1080/02713683.2016.1221979?scroll=top&needAccess=true


  • Myopia control

The effects of entrance pupil centration and coma aberrations on myopic progression following orthokeratology

Jacinto Santodomingo Rubido et al.

The study was conducted in Spain to assess the potential association between entrance pupil location relative to the coaxially sighted corneal light reflex (CSCLR) and the progression of myopia in children fitted with orthokeratology (OK) and to investigate whether coma aberration induced by decentration of the entrance pupil centre relative to the CSCLR, as well as following OK treatment, is correlated with the progression of myopia. A significant increase in vertical coma was found with OK lens wear compared to baseline (p < 0.001) but total root mean square (RMS) coma was not associated with the change in axial length (all p > 0.05). Entrance pupil location relative to the CSCLR was not significantly affected by either OK lens wear or an increase in axial length. Greater magnitude coma aberrations found at the entrance pupil centre in comparison to the CSCLR might be attributed to centration of orthokeratological treatments at the CSCLR.

https://onlinelibrary.wiley.com/doi/full/10.1111/cxo.12297


  • Myopia control

Effect of low-addition soft contact lenses with decentered optical design on myopia progression in children: a pilot study

Takashi Fujikado et al.

The pilot study was conducted to evaluate the effect of decentered optical design low-addition soft contact lenses for controlling myopia progression over 2 years. Control group wore monofocal soft contact lenses. As a result of this study, it was observed that the decentered optical design low-addition soft contact lenses was effective to suppress the axial elongation compared to control group, however, we did not find significant difference on refractive error.
The reduction of the progression of myopia by low-addition soft CLs warrants further investigations.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181743/


  • Myopia control

Factors Preventing Myopia Progression With Orthokeratology Correction

Jacinto Santodomingo-Rubido et al

The study was conducted in Spain to examine which baseline measurements constitute predictive factors for axial length growth over 2 years in children wearing orthokeratology contact lenses (ortho-k) and single-vision spectacles (SV). Orthokeratology is a successful treatment option in controlling axial elongation compared to SV in children of older age, had earlier onset of myopia, were female, had lower rate of myopia progression before baseline, had lower myopia at baseline, had longer anterior chamber depth, had greater corneal power, had more prolate corneal shape, had larger iris and pupil diameters, and had lower levels of parental myopia.

https://journals.lww.com/optvissci/pages/articleviewer.aspx?year=2013&issue=11000&article=00012&type=abstract


  • Myopia control

Myopia Control with Orthokeratology Contact Lenses in Spain (MCOS): Refractive and Biometric Changes

Jacinto Santodomingo-Rubido et al

The study was conducted for 2 years in Spain, for the purpose of comparing axial length growth between white children with myopia wearing orthokeratology contact lenses (ortho-k) and distance single-vision spectacles (SV). The axial length growth was observed with both groups, however, that of SV group was significantly greater than ortho-k group. This result showed the ortho-k lowered the axial length growth and might be effective to control the myopia progression.
Open Access https://iovs.arvojournals.org/article.aspx?articleid=2168338

https://iovs.arvojournals.org/article.aspx?articleid=2168338


  • Myopia control

Retardation of Myopia in Orthokeratology (ROMIO) Study: A 2-Year Randomized Clinical Trial

Pauline Cho; Sin-Wan Cheung

The study was conducted for 2 years in Hong Kong, for the purpose to evaluate the effectiveness of orthokeratology contact lenses (ortho-k), which is thought to be one of the means for the myopia progression control. One group was assigned to wear ortho-k, and the other to wear single-vision glasses as a control. As a result of measuring the axial length, the axial length elongation of ortho-k group was 43% slower than of the control group, so that the ortho-k might be effective to control the myopia progression.

https://iovs.arvojournals.org/article.aspx?articleid=2127470

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